Abstract
The data from this study indicate that cefoxitin was effective and generally well tolerated in the management of gangrenous and/or perforated appendicitis. No strong correlation was identified between in vitro susceptibility testing results and clinical outcome.
MeSH terms
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Appendicitis / complications
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Appendicitis / drug therapy*
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Appendicitis / microbiology
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Bacteroides fragilis / drug effects
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Cefoxitin / therapeutic use*
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Ceftizoxime / therapeutic use*
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Double-Blind Method
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Gangrene
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Humans
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Intestinal Perforation / etiology
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Microbial Sensitivity Tests
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Prospective Studies
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Rupture, Spontaneous