Multifunctional poly(alkyl methacrylate) films for dental care

Biomed Mater. 2011 Feb;6(1):015003. doi: 10.1088/1748-6041/6/1/015003. Epub 2011 Jan 5.

Abstract

Towards the evaluation of non-permanent dental coatings for their capacity to impart dental-care benefits, thin films of a homologous series of comb-like poly(alkyl methacrylate)s (ethyl to octadecyl) have been deposited, from aqueous latex formulations, onto dentally relevant substrates. AFM studies have shown that the thickness (40-300 nm) and surface roughness (8-12 nm) of coherent polymer films are influenced by the degree of polymerization and by the length of the pendant chain. Of the polymers under consideration, poly(butyl methacrylate) formed a close-packed film that conferred to dental substrates a high degree of inhibition to acid-mediated erosion (about 27%), as evaluated by released-phosphate determinations. The potential utility of the coatings to act as anti-sensitivity barriers has been evaluated by determining the hydraulic conductance of coated bovine-dentine substrates; single treatments of dentine discs with poly(butyl methacrylate) or with poly(ethyl methacrylate) effected mean respective reductions in fluid flow of about 23% with respect to water-treated controls; repeated applications of the poly(butyl methacrylate) latex led to mean reductions in fluid flow of about 80%. Chromometric measurements have shown that pellicle-coated hydroxyapatite discs treated with poly(butyl methacrylate), poly(hexyl methacrylate) or poly(lauryl methacrylate) exhibit significant resistance to staining by food chromogens.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • Coated Materials, Biocompatible / chemistry
  • Dental Enamel Permeability
  • Dental Materials / chemistry*
  • Dentin Sensitivity / prevention & control
  • Durapatite / chemistry
  • Humans
  • In Vitro Techniques
  • Materials Testing
  • Microscopy, Atomic Force
  • Models, Dental
  • Polymethacrylic Acids / chemistry*
  • Tooth Demineralization / prevention & control
  • Tooth Discoloration / prevention & control
  • Tooth Erosion / prevention & control

Substances

  • Coated Materials, Biocompatible
  • Dental Materials
  • Polymethacrylic Acids
  • polybutyl methacrylate
  • Durapatite