Objective: To investigate the prevalence of peripheral arterial disease (PAD) and its correlative risk factors in Xinjiang Uygur and Kazak adult populations.
Methods: The subjects over the age of 35 years old in Urumqi, Karamay City, Fukang City, Turpan Region, Hotan Prefecture and Yili Kazak Autonomous Prefecture were selected by the four-stage random sampling method. The investigators collected the data of PAD prevalence in different nationalities, different age groups and different gender groups and analyzed its risk factors.
Results: The prevalence of PAD in Uygur and Kazak adults was 6.46% (n = 542). The standardized prevalence was 6.51%. The prevalence of PAD was 7.05% (n = 315) in Uygur adults and 5.79% (n = 227) in Kazak adults. The standardized prevalence in the Uygur and Kazak adults was 7.08% and 5.83% respectively. The prevalence of PAD of different nationalities was different (χ(2) = 5.55, P < 0.05). And its prevalence was 4.49% (n = 170) in males and 8.08% (n = 372) in females. The standardized prevalence was 4.30% in males and 7.90% in females. The prevalence of PAD in males and females was significantly different (χ(2) = 44.26, P < 0.01). The multivariate logistic regression analysis was performed. Age (OR = 1.01, 95%CI 1.00 - 1.02), females (OR = 1.75, 95%CI 1.45 - 2.14), overweight or obesity (OR = 1.04, 95%CI 1.01 - 1.06), diabetes (OR = 1.59, 95%CI 1.01 - 2.36), elevated systolic blood pressure (OR = 1.02, 95%CI 1.01 - 1.03), elevated diastolic blood pressure (OR = 1.08, 95%CI 1.01 - 1.11) and history of coronary heart disease (OR = 1.69, 95%CI 1.14 - 2.50) were associated with an elevated prevalence of PAD.
Conclusion: The prevalence of PAD is lower in Xinjiang Uygur and Kazak adult populations. Females, age, overweight or obesity, diabetes, elevated systolic blood pressure and a history of coronary heart disease are risk factors of PAD.