Efficacy of eprinomectin pour-on against Dictyocaulus arnfieldi infection in donkeys (Equus asinus)

Vet J. 2011 Dec;190(3):414-5. doi: 10.1016/j.tvjl.2010.11.024. Epub 2011 Jan 7.

Abstract

A trial to assess the efficacy of eprinomectin (EPM) against the lungworm Dictyocaulus arnfieldi was carried out on 15, naturally-infected donkeys. Ten animals were treated with a 'pour-on' EPM preparation (at a dose of 0.5 mg/kg bodyweight), and five animals acted as controls. Faecal larval counts were carried out two days before treatment, on day of treatment and 7, 14, 21 and 28 days post-treatment with the anthelmintic. EPM was 100% effective in eliminating faecal larvae from day 7, until the end of study at day 28. No adverse drug-reactions or side-effects were observed in any of the treated donkeys.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Animals
  • Anthelmintics / administration & dosage*
  • Dictyocaulus / drug effects*
  • Dictyocaulus / isolation & purification
  • Dictyocaulus Infections / drug therapy*
  • Dose-Response Relationship, Drug
  • Equidae / parasitology*
  • Feces / parasitology
  • Ivermectin / administration & dosage
  • Ivermectin / analogs & derivatives*
  • Treatment Outcome

Substances

  • Anthelmintics
  • Ivermectin
  • eprinomectin