Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11

J Ellis; M Galiano; R Pebody; A Lackenby; C Thompson; A Bermingham; E McLean; H Zhao; S Bolotin; O Dar; J M Watson; M Zambon

Virological analysis of fatal influenza cases in the United Kingdom during the early wave of influenza in winter 2010/11

Euro Surveill. 2011 Jan 6;16(1):19760.

Authors

J Ellis¹, M Galiano, R Pebody, A Lackenby, C Thompson, A Bermingham, E McLean, H Zhao, S Bolotin, O Dar, J M Watson, M Zambon

Affiliation

¹ Health Protection Agency, Centre for Infections, London, United Kingdom.

PMID: 21223836

Abstract

The 2010/11 winter influenza season is underway in the United Kingdom, with co-circulation of influenza A(H1N1)2009 (antigenically similar to the current 2010/11 vaccine strain), influenza B (mainly B/Victoria/2/87 lineage, similar to the 2010/11 vaccine strain) and a few sporadic influenza A(H3N2) viruses. Clinical influenza activity has been increasing. Severe illness, resulting in hospitalisation and deaths, has occurred in children and young adults and has predominantly been associated with influenza A(H1N1)2009, but also influenza B viruses.

Publication types

Case Reports

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Antigens, Viral / genetics
Child
Disease Outbreaks
Female
Genotype
Hospitalization
Humans
Influenza A Virus, H1N1 Subtype / genetics*
Influenza A Virus, H1N1 Subtype / immunology
Influenza A Virus, H1N1 Subtype / isolation & purification
Influenza B virus / genetics*
Influenza B virus / immunology
Influenza B virus / isolation & purification
Influenza Vaccines / immunology
Influenza, Human / diagnosis
Influenza, Human / mortality*
Influenza, Human / prevention & control
Influenza, Human / virology*
Male
Middle Aged
Phenotype
Phylogeny
Seasons
Sentinel Surveillance
Sequence Analysis, DNA
Severity of Illness Index
United Kingdom / epidemiology
Young Adult

Substances

Antigens, Viral
Influenza Vaccines