[A clinical case of lymph node recurrence after resection of gastric cancer successfully treated by combination chemotherapy with irinotecan and cisplatin]

Gan To Kagaku Ryoho. 2010 Nov;37(12):2418-20.
[Article in Japanese]

Abstract

A 60-year-old female who was diagnosed as gastric cancer underwent distal gastrectomy and received adjuvant chemotherapy (S-1 therapy). After 6 months, the tumor marker (CEA) was elevated. CT revealed para-aortic lymph nodes enlargement. Lymph node metastasis was confirmed. The patient was administered combination chemotherapy with irinotecan (CPT-11) and cisplatin (CDDP) Seven months later, CT revealed lymph node metastasis had disappeared. After judgment of complete response (CR), we continued the treatment for 22 months. The patient was followed without any recurrence in May 2010.

Publication types

  • Case Reports

MeSH terms

  • Antimetabolites, Antineoplastic / therapeutic use
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents, Phytogenic / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Camptothecin / administration & dosage
  • Camptothecin / analogs & derivatives
  • Cisplatin / administration & dosage
  • Drug Combinations
  • Female
  • Gastrectomy
  • Humans
  • Irinotecan
  • Lymph Node Excision
  • Lymphatic Metastasis / pathology
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Oxonic Acid / therapeutic use
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / surgery
  • Tegafur / therapeutic use

Substances

  • Antimetabolites, Antineoplastic
  • Antineoplastic Agents
  • Antineoplastic Agents, Phytogenic
  • Drug Combinations
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid
  • Irinotecan
  • Cisplatin
  • Camptothecin