Perivascular epithelioid cell neoplasm of the uterine cervix: an unusual tumor in an unusual location

Rare Tumors. 2010 Dec 31;2(4):e56. doi: 10.4081/rt.2010.e56.

Abstract

A 46-year-old woman presented for a second opinion regarding a 3-4 cm mass of the uterine cervix. A prior biopsy had been interpreted as a malignant melanoma of the cervix, resulting in a radical hysterectomy with bilateral salpingooophorectomy. This was to be followed by external beam irradiation and immunotherapy; however, given the rarity of this diagnosis, the patient sought a second opinion at our institution. Further review of the pathological material from the hysterectomy revealed a morphologically benign perivascular epithelioid cell neoplasm rather than a malignant melanoma. Close monitoring of the patient was recommended; she is currently diseasefree more than three years after her initial presentation.

Keywords: gynecological neoplasms.; immunohistochemistry; melanoma; perivascular epithelioid cell neoplasm.

Publication types

  • Case Reports