Abstract
Patients with myasthenia gravis and thymoma usually present antibodies to the acetylcholine receptor (AchR-Ab). Only two cases of thymoma-associated myasthenia gravis without AchR-Ab have been previously reported. We describe a case of seronegative thymoma-associated myasthenia gravis as a further evidence of the variability of myasthenia gravis in terms of antibody profile and thymic pathological findings.
Copyright © 2010. Published by Elsevier B.V.
MeSH terms
-
Action Potentials / physiology
-
Anti-Inflammatory Agents / therapeutic use
-
Autoantibodies
-
Azathioprine / therapeutic use
-
Electric Stimulation
-
Evoked Potentials, Motor / physiology
-
Fatal Outcome
-
Humans
-
Immunosuppressive Agents / therapeutic use
-
Male
-
Middle Aged
-
Muscle Weakness / etiology
-
Muscle, Skeletal / physiology
-
Myasthenia Gravis / complications*
-
Myasthenia Gravis / immunology
-
Neurologic Examination
-
Prednisone / therapeutic use
-
Radioimmunoassay
-
Receptors, Cholinergic / immunology*
-
Thymoma / complications*
-
Thymoma / immunology
-
Thymus Neoplasms / complications*
-
Thymus Neoplasms / immunology
-
Tomography, X-Ray Computed
Substances
-
Anti-Inflammatory Agents
-
Autoantibodies
-
Immunosuppressive Agents
-
Receptors, Cholinergic
-
Azathioprine
-
Prednisone