Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia

Oana L Klein; Lewis J Smith; Matthew Tipping; Jie Peng; Mark V Williams

doi:10.1016/j.diabres.2010.12.012

Reduced diffusion lung capacity in patients with type 2 diabetes mellitus predicts hospitalization for pneumonia

Diabetes Res Clin Pract. 2011 Apr;92(1):e12-5. doi: 10.1016/j.diabres.2010.12.012. Epub 2011 Jan 14.

Authors

Oana L Klein¹, Lewis J Smith, Matthew Tipping, Jie Peng, Mark V Williams

Affiliation

¹ Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States. [email protected]

PMID: 21237523
DOI: 10.1016/j.diabres.2010.12.012

Abstract

Among 4164 patients, those with type 2 diabetes mellitus (DM) had lower lung diffusion capacity (DLCO) compared with those without DM (DLCO mean±SE: 15.7±0.3 vs. 17.0±0.2 mL/min/mm Hg, p<0.01). Reduced DLCO predicted hospitalization for pneumonia independent of diabetes control, severity and co-morbidities (OR=2.4, CI 1.08-5.31).

MeSH terms

Aged
Diabetes Mellitus, Type 2 / physiopathology*
Female
Heart Failure / physiopathology
Hospitalization / statistics & numerical data*
Humans
Lung Volume Measurements*
Male
Middle Aged
Pneumonia / physiopathology*