The preparation of glutathione-capped CdTe quantum dots and their use in imaging of cells

Mei Xue; Xu Wang; Hui Wang; Bo Tang

doi:10.1016/j.talanta.2010.11.064

The preparation of glutathione-capped CdTe quantum dots and their use in imaging of cells

Talanta. 2011 Feb 15;83(5):1680-6. doi: 10.1016/j.talanta.2010.11.064. Epub 2010 Nov 30.

Authors

Mei Xue¹, Xu Wang, Hui Wang, Bo Tang

Affiliation

¹ College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Shandong Normal University, Jinan, People's Republic of China.

PMID: 21238768
DOI: 10.1016/j.talanta.2010.11.064

Abstract

In this paper, different sizes of glutathione-capped CdTe (GSH/CdTe) quantum dots (QDs) have been prepared directly in aqueous solution. The QDs have tunable fluorescence in the range of 510-670 nm, and they also have high photoluminescence quantum yield (PLQY) without any postpreparative treatment. Furthermore, the QDs have strong resistance to photobleaching, and they also have to be considered as cytocompatible. In addition, for the first time, folic acid was covalently conjugated to the GSH/CdTe QDs for imaging of cancer cells, demonstrating their potentially broad application as biolabels.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cadmium Compounds* / chemistry
Cadmium Compounds* / pharmacology
Cell Survival / drug effects
Diagnostic Imaging
Fluorescence
Glutathione* / chemistry
Glutathione* / pharmacology
Hep G2 Cells
Humans
Quantum Dots*
Tellurium* / chemistry
Tellurium* / pharmacology
Water / chemistry*

Substances

Cadmium Compounds
Water
Glutathione
Tellurium
cadmium telluride