Transposition of greater omentum in deep sternal wound infection caused by methicillin-resistant Staphylococci, with differing clinical course for MRSA and MRSE

Thorac Cardiovasc Surg. 2011 Feb;59(1):21-4. doi: 10.1055/s-0030-1250373. Epub 2011 Jan 17.

Abstract

Background: Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis (MRSE) are an increasing problem in deep sternal wound infections (DSWI) after cardiac surgery.

Methods: Between 2005 and 2009, recalcitrant methicillin-resistant Staphylococcus was found in 21 patients with complicated DSWI, and a transposition of the greater omentum (TGO) was finally performed. A positive microbial culture at the time of procedure was present in all patients. The hospital course was reviewed discretely for MRSA and MRSE.

Results: Median patient age was 72.3 years (range 60.8-79.7); 76 % of patients were male. Time from the first sternal revision until consecutive open wound therapy due to re-infection and total hospital stay was longer for MRSA compared to MRSE (38 vs. 14 days, P = 0.003, and 141 vs. 91 days, P = 0.007, respectively). The period from cardiac surgery to TGO was likewise prolonged for MRSA (78 vs. 55 days, P = 0.045), whereas in-hospital mortality and one-year mortality rate did not differ.

Conclusion: TGO remains a good treatment option for DSWI type IV. Microbial findings determine the clinical course; nevertheless in-hospital mortality remains low for both MRSA and MRSE infection.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cardiac Surgical Procedures / adverse effects
  • Female
  • Humans
  • Length of Stay
  • Male
  • Methicillin Resistance*
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification*
  • Microbial Sensitivity Tests
  • Middle Aged
  • Omentum / transplantation*
  • Plastic Surgery Procedures / methods*
  • Retrospective Studies
  • Staphylococcal Infections / complications*
  • Staphylococcal Infections / mortality
  • Staphylococcal Infections / surgery
  • Staphylococcus epidermidis / isolation & purification
  • Sternotomy / adverse effects*
  • Surgical Wound Infection / microbiology*
  • Surgical Wound Infection / mortality
  • Surgical Wound Infection / surgery
  • Survival Analysis
  • Thoracic Surgical Procedures* / methods
  • Treatment Outcome