[Clinical and biological correlations of esophageal varices in patients with compensated hepatic cirrhosis]

Rev Med Chir Soc Med Nat Iasi. 2010 Jul-Sep;114(3):671-6.
[Article in Romanian]

Abstract

Material and methods: The retrospective study included 126 patients with hepatic cirrhosis (HC) CHILD A class, assisted in Botoşani Hospital, during 2007 and 2008. Patients were clinic, biochemical, hematological, etiological, ultrasonographic, endoscopical examined. Statistical analysis carried out with EXCEL soft and SPSS 16.0 soft, calculating chi2, p, ROC curve, SPRI and ASPRI values.

Results: We assessed the sample characteristics using the univariate analysis: age, the presence/absence of esophageal varices, SPRI score (limit value > or = 15.5), ASPRI score (limit value > or = 19.3).

Conclusions: Non-invasive prediction cannot exclude the endoscopic exam in patients with compensated HC, caused especially by the virus C and alcohol consumption. Thrombocytopenia and splenomegaly and Fibroscan exam were the best noninvasive indicators to predict the esophageal varices.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Elasticity Imaging Techniques / methods
  • Esophageal and Gastric Varices / blood
  • Esophageal and Gastric Varices / diagnosis*
  • Esophageal and Gastric Varices / etiology
  • Female
  • Humans
  • Liver Cirrhosis / blood
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / diagnosis*
  • Liver Function Tests
  • Male
  • Middle Aged
  • Platelet Count
  • Predictive Value of Tests
  • ROC Curve
  • Retrospective Studies
  • Risk Factors
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Splenomegaly / diagnosis