Abstract
Ritonavir therapy is not generally considered nephrotoxic. We report a case of acute kidney injury secondary to ritonavir, with kidney biopsy demonstrating extensive acute tubular injury. This is the first report of a kidney biopsy and pathology in acute kidney injury associated with ritonavir. A review of published medical literature on the topic is also presented.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Acute Kidney Injury / chemically induced*
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Acute Kidney Injury / pathology
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Antiretroviral Therapy, Highly Active
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Biomarkers / blood
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Biopsy
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Creatinine / blood
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Drug Substitution
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HIV Infections / drug therapy*
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HIV Protease Inhibitors / adverse effects*
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Humans
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Kidney / drug effects*
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Kidney / pathology
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Kidney Tubules / drug effects
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Kidney Tubules / pathology
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Male
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Middle Aged
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Ritonavir / adverse effects*
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Time Factors
Substances
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Biomarkers
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HIV Protease Inhibitors
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Creatinine
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Ritonavir