Abstract
The ViroSeq HIV-1 genotyping system is used in many African countries for drug resistance testing. In this study, we used a panel of diverse HIV-1 group M isolates circulating in Cameroon to show that the performance of this assay can be altered by the sequence variation of non-B HIV-1 strains that predominate in African settings.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Cameroon
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Drug Resistance, Viral
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Genetic Variation*
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Genotype
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HIV Infections / virology*
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HIV-1 / classification*
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HIV-1 / genetics*
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HIV-1 / isolation & purification
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Humans
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Microbial Sensitivity Tests / methods
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Molecular Sequence Data
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Molecular Typing / methods*
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Sensitivity and Specificity
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Sequence Analysis, DNA