Abstract
A one-pot synthesis of tetrahydroisoquinoline alkaloids in a phosphate buffer has been achieved, and a reaction mechanism proposed. The utilisation of mild reaction conditions readily afforded a range of isoquinolines, including norcoclaurine.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemistry
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Alkaloids / chemical synthesis
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Alkaloids / chemistry
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Biomimetics
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Dopamine / chemistry
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Hydrogen-Ion Concentration
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Phosphates / chemistry*
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Stereoisomerism
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Tetrahydroisoquinolines / chemical synthesis
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Tetrahydroisoquinolines / chemistry*
Substances
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Aldehydes
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Alkaloids
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Phosphates
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Tetrahydroisoquinolines
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higenamine
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Dopamine