A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases

Leukemia. 2011 Mar;25(3):557-60. doi: 10.1038/leu.2010.298. Epub 2011 Jan 28.
No abstract available

Publication types

  • Letter

MeSH terms

  • Blast Crisis / genetics*
  • Chromosome Aberrations
  • Core Binding Factor Alpha 2 Subunit / genetics
  • Fusion Proteins, bcr-abl / genetics
  • Genes, Wilms Tumor
  • Humans
  • Ikaros Transcription Factor / genetics
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics*
  • Mutation*
  • Repressor Proteins / genetics

Substances

  • ASXL1 protein, human
  • Core Binding Factor Alpha 2 Subunit
  • IKZF1 protein, human
  • RUNX1 protein, human
  • Repressor Proteins
  • Ikaros Transcription Factor
  • Fusion Proteins, bcr-abl