Strategies towards improving the pharmacokinetic profile of ε-substituted lysinol-derived HIV protease inhibitors

ChemMedChem. 2011 Feb 7;6(2):253-7. doi: 10.1002/cmdc.201000395. Epub 2010 Dec 29.
No abstract available

MeSH terms

  • Antiretroviral Therapy, Highly Active
  • HIV Infections / drug therapy
  • HIV Protease Inhibitors / chemistry
  • HIV Protease Inhibitors / pharmacokinetics*
  • HIV Protease Inhibitors / therapeutic use
  • Lysine / chemistry*
  • Structure-Activity Relationship

Substances

  • HIV Protease Inhibitors
  • Lysine