[The model of the two-hit of Knudson applies to the auto-immune diseases: the example of the lymphoproliferative syndrome with auto-immunity]

MeSH terms

• Apoptosis
• Autoimmune Diseases / etiology*
• Autoimmune Diseases / immunology
• Autoimmune Lymphoproliferative Syndrome / etiology
• Autoimmune Lymphoproliferative Syndrome / genetics
• Autoimmune Lymphoproliferative Syndrome / immunology
• Cells, Cultured / immunology
• Cells, Cultured / pathology
• Chromosome Deletion
• Chromosomes, Human, Pair 10 / genetics
• Chromosomes, Human, Pair 10 / ultrastructure
• Epistasis, Genetic
• Fas Ligand Protein / physiology
• Genotype
• Germ-Line Mutation
• Humans
• Models, Genetic
• Models, Immunological*
• Penetrance
• T-Lymphocyte Subsets / immunology
• fas Receptor / deficiency
• fas Receptor / genetics
• fas Receptor / physiology