Development of artificial placenta: oxygen metabolism of isolated goat fetuses with umbilical arteriovenous extracorporeal membrane oxygenation

Fetal Diagn Ther. 1990;5(3-4):189-95. doi: 10.1159/000263592.

Abstract

To assess the oxygen utilization of extrauterine goat fetuses with arteriovenous extracorporeal membrane oxygenation via umbilical vessels, oxygen delivery (OD) and oxygen consumption (OC) were investigated in 19 long-term incubations (incubation periods 58-236 h). The OCs did not change (6.4 +/- 1.3 ml/min/kg, mean +/- SD, n = 227) when the ODs were more than 10 ml/min/kg, but were significantly suppressed when the ODs were less than 10 ml/min/kg. It was suggested that the oxygen metabolism of extrauterine goat fetuses is equivalent to that of fetuses in utero.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Artificial Organs*
  • Extracorporeal Membrane Oxygenation*
  • Fetus / metabolism*
  • Goats
  • Oxygen / blood
  • Oxygen Consumption*
  • Placenta*
  • Umbilical Arteries
  • Umbilical Veins

Substances

  • Oxygen