Abstract
A convergent synthesis of the C1-C16 segment of goniodomin A, an actin-targeting marine polyether macrolide natural product, has been achieved via a 2-fold application of palladium-catalyzed organostannane-thioester coupling.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Actins / metabolism
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Catalysis
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Esters
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Ethers / chemical synthesis*
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Ethers / chemistry
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Ethers / pharmacology
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Macrolides / chemical synthesis*
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Macrolides / chemistry
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Macrolides / pharmacology
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Molecular Structure
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Organotin Compounds / chemistry*
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Palladium / chemistry*
Substances
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Actins
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Esters
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Ethers
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Macrolides
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Organotin Compounds
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goniodomin A
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Palladium