Abstract
A 63-year-old women had an extensive limbal papilliform tumoural lesion of her left eye. Mitomycin C (MMC) was applied to the area at a dose of 0.2 mg/ml after total surgical excision of the lesion. The lesion was diagnosed as invasive squamous cell carcinoma on histopathology and topical 0.02% MMC was prescribed four times daily to the left eye. A severe per ocular contact dermatitis of the left eye developed two days after starting MMC. The patch test result was positive. The per ocular dermatitis resolved after discontinuation of the topical MMC and treatment with a topical corticosteroid.
MeSH terms
-
Administration, Topical
-
Adrenal Cortex Hormones / administration & dosage
-
Adrenal Cortex Hormones / therapeutic use
-
Antibiotics, Antineoplastic / administration & dosage
-
Antibiotics, Antineoplastic / adverse effects*
-
Antibiotics, Antineoplastic / therapeutic use
-
Carcinoma, Squamous Cell / drug therapy
-
Carcinoma, Squamous Cell / pathology
-
Conjunctival Neoplasms / drug therapy
-
Conjunctival Neoplasms / pathology
-
Dermatitis, Allergic Contact / diagnosis
-
Dermatitis, Allergic Contact / drug therapy
-
Dermatitis, Allergic Contact / etiology*
-
Dermatitis, Perioral / chemically induced*
-
Dermatitis, Perioral / diagnosis
-
Dermatitis, Perioral / drug therapy
-
Female
-
Humans
-
Middle Aged
-
Mitomycin / administration & dosage
-
Mitomycin / adverse effects*
-
Mitomycin / therapeutic use
-
Ophthalmic Solutions
-
Treatment Outcome
Substances
-
Adrenal Cortex Hormones
-
Antibiotics, Antineoplastic
-
Ophthalmic Solutions
-
Mitomycin