Isolated central nervous system relapse after nine years of complete molecular remission in a lymphoid blast crisis of chronic myeloid leukemia treated with imatinib

MeSH terms

• Aged
• Antineoplastic Agents / therapeutic use
• Benzamides
• Blast Crisis / drug therapy
• Blast Crisis / genetics
• Central Nervous System / pathology*
• Female
• Fusion Proteins, bcr-abl / genetics
• Humans
• Imatinib Mesylate
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy*
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
• Piperazines / therapeutic use*
• Pyrimidines / therapeutic use*
• Recurrence
• Remission Induction
• Reverse Transcriptase Polymerase Chain Reaction