Abstract
We describe a 14-year-old boy who exhibited left palatine tonsillar enlargement after 6 cycles of aggressive chemotherapy for diffuse large B-cell lymphoma of the right palatine tonsil. The cervical computed tomography scan at 4 months after completion of chemotherapy revealed enlargement of the left palatine tonsil in addition to the thymus without any clinical symptoms. The F-fluorodeoxyglucose positron emission tomography indicated focal areas of strong F-fluorodeoxyglucose uptake in the left palatine tonsil. Histologic examination confirmed tonsillar hyperplasia with no evidence of recurrence. Reactive tonsillar hyperplasia after chemotherapy is rarely reported.
MeSH terms
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Adolescent
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Cyclophosphamide / administration & dosage
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Cytarabine / administration & dosage
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Dexamethasone / administration & dosage
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Doxorubicin / administration & dosage
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Doxorubicin / analogs & derivatives
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Etoposide / administration & dosage
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Fluorodeoxyglucose F18
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Humans
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Hyperplasia / pathology
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Lymphoma, Large B-Cell, Diffuse / diagnostic imaging
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
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Lymphoma, Large B-Cell, Diffuse / pathology
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Male
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Methotrexate / administration & dosage
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Neoplasm Staging
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Palatine Tonsil / diagnostic imaging*
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Palatine Tonsil / drug effects
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Palatine Tonsil / pathology*
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Positron-Emission Tomography
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Prednisolone / administration & dosage
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Radiopharmaceuticals
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Tonsillar Neoplasms / diagnostic imaging
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Tonsillar Neoplasms / drug therapy*
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Tonsillar Neoplasms / pathology
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Vincristine / administration & dosage
Substances
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Radiopharmaceuticals
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Cytarabine
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Fluorodeoxyglucose F18
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Vincristine
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Etoposide
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Dexamethasone
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Doxorubicin
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Cyclophosphamide
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Prednisolone
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pirarubicin
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Methotrexate