Cancer of prostate: relief of bone pain with levodopa

N Sadoughi; M Razvi; I Bush; R Ablin; P Guinan

doi:10.1016/0090-4295(74)90121-6

Cancer of prostate: relief of bone pain with levodopa

Urology. 1974 Jul;4(1):107-8. doi: 10.1016/0090-4295(74)90121-6.

Authors

N Sadoughi¹, M Razvi, I Bush, R Ablin, P Guinan

Affiliation

¹ Division of Urology, University of Health Sciences, The Chicago Medical School, Illinois, USA.

PMID: 21322998
DOI: 10.1016/0090-4295(74)90121-6

Abstract

Six patients with metastatic carcinoma of the prostate were given 250 to 500 mg. of levodopa at four-hour intervals for bone pain. Four patients showed definite improvement. Based on our observation, further trial of levodopa is recommended for relief of bone pain in patients with metastatic carcinoma of the prostate.

MeSH terms

Bone Neoplasms / complications*
Bone Neoplasms / secondary*
Humans
Levodopa / therapeutic use*
Male
Pain / drug therapy*
Pain / etiology*
Prostatic Neoplasms / pathology*

Substances

Levodopa