Abstract
Advances in imaging technology have provided powerful tools for dissecting the angiogenic and inflammatory aspects of atherosclerosis. Improved technology along with multi-modal approaches has expanded the utilisation of imaging. Recent advances provide the ability to better define structure and development of angiogenic vessels, identify relationships between inflammatory mediators and the vessel wall, validate biological effects of anti-inflammatory and anti-angiogenic drugs, delivery and/or targeting specific molecules to inflammatory regions of atherosclerotic plaques.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Angiogenesis Inhibitors / pharmacology
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Angiogenesis Inhibitors / therapeutic use
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Animals
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Anti-Inflammatory Agents / pharmacology
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Anti-Inflammatory Agents / therapeutic use
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Atherosclerosis / diagnosis*
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Atherosclerosis / drug therapy
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Atherosclerosis / immunology
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Atherosclerosis / pathology*
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Endothelium, Vascular / drug effects
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Endothelium, Vascular / pathology*
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Humans
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Inflammation Mediators / metabolism
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Inflammation*
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Neovascularization, Pathologic*
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Plaque, Atherosclerotic
Substances
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Angiogenesis Inhibitors
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Anti-Inflammatory Agents
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Inflammation Mediators