Setting sample size to ensure narrow confidence intervals for precise estimation of population values

Nurs Res. 2011 Mar-Apr;60(2):148-53. doi: 10.1097/NNR.0b013e318209785a.

Abstract

Background: Sample sizes set on the basis of desired power and expected effect size are often too small to yield a confidence interval narrow enough to provide a precise estimate of a population value.

Approach: Formulae are presented to achieve a confidence interval of desired width for four common statistical tests: finding the population value of a correlation coefficient (Pearson r), the mean difference between two populations (independent- and dependent-samples t tests), and the difference between proportions for two populations (chi-square for contingency tables).

Discussion: Use of the formulae is discussed in the context of the two goals of research: (a) determining whether an effect exists and (b) determining how large the effect is. In addition, calculating the sample size needed to find a confidence interval that captures the smallest benefit of clinical importance is addressed.

MeSH terms

  • Bias
  • Chi-Square Distribution
  • Confidence Intervals*
  • Data Interpretation, Statistical*
  • Effect Modifier, Epidemiologic
  • Humans
  • Linear Models
  • Multivariate Analysis
  • Nursing Research / methods*
  • Reproducibility of Results
  • Research Design
  • Sample Size*