Abstract
Thickness does matter! The ultrathin nature of 1.8 nm-thick Pd nanosheets prevents them entering cells effectively. A 13-times enhancement in the cells' uptake of the Pd nanosheets has now been achieved by silica coating together with surface functionalization, therefore significantly improving their NIR photothermal cell-killing efficacy.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Line, Tumor
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Cell Survival / drug effects
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Humans
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Low-Level Light Therapy / methods*
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Nanostructures / chemistry
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Nanostructures / therapeutic use*
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Neoplasms / radiotherapy*
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Palladium / chemistry
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Palladium / therapeutic use*
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Silicon Dioxide / chemistry
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Silicon Dioxide / therapeutic use*
Substances
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Palladium
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Silicon Dioxide