Abstract
This study aimed to evaluate the accuracy of routine systems (Vitek2 cards AST-N022 and AST-N026; Kirby Bauer; Etest) for susceptibility testing of Pseudomonas aeruginosa to piperacillin and piperacillin-tazobactam. Vitek2 (card AST-N022) showed the worst performance; the other three methods (Vitek2 card AST-N026, Kirby-Bauer and E-test) performed comparably but never fulfilled the minimal standard proposed by FDA.
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Bacteriological Techniques / methods
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Bacteriological Techniques / standards
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Humans
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Microbial Sensitivity Tests / methods
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Microbial Sensitivity Tests / standards*
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Penicillanic Acid / analogs & derivatives
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Penicillanic Acid / pharmacology
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Piperacillin / pharmacology*
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Piperacillin, Tazobactam Drug Combination
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Predictive Value of Tests
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Pseudomonas Infections / microbiology
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Pseudomonas aeruginosa / drug effects*
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Pseudomonas aeruginosa / isolation & purification
Substances
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Anti-Bacterial Agents
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Piperacillin, Tazobactam Drug Combination
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Penicillanic Acid
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Piperacillin