Prevalence of specific herpes simplex virus-2 antibodies and associated factors in women of a rural town of Colombia

Trans R Soc Trop Med Hyg. 2011 Apr;105(4):232-8. doi: 10.1016/j.trstmh.2011.01.004. Epub 2011 Feb 25.

Abstract

There is lack of age-specific seroprevalence surveys and identification of factors associated with herpes simplex virus type-2 seropositivity (HSV-2) in rural populations in Colombia. A random sample of 869 women was interviewed about socio-demographic aspects, sexual and reproductive history. Antibodies to HSV-2 were determined by a specific type immunoenzymatic technique (ELISA). Participants had a mean age of 38±16.1 years, 67% were married, 60% monogamous and 47% reported use of condoms. HSV-2 seroprevalence was 19.1% (95% CI: 16.6-21.9) and it was strongly associated with increasing age (Ptrend<0.001). In the logistic regression analysis, women who reported between two or three lifetime sexual partners (OR=2.4; 95% CI: 1.5-3.7), >31 years of sexual activity with regular or occasional sexual partners (OR=4.3; 95% CI: 1.2-15.7) and not using condoms with regular sexual partners (OR=2.1; 95% CI: 1.4-3.3) were more likely to be HSV-2 seropositive. The overall seroprevalence rate of women of Pueblorrico, Colombia, is lower than that reported in other Latin American countries especially in women>45 years. The difference may be explained by higher prevalence of condom use in this population or lower exposure to herpes infection in male as well as females in the past.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Viral / blood*
  • Colombia / epidemiology
  • Female
  • Herpes Genitalis / epidemiology
  • Herpes Genitalis / immunology*
  • Herpes Genitalis / transmission
  • Herpesvirus 2, Human / immunology*
  • Humans
  • Interviews as Topic
  • Physical Examination
  • Prevalence
  • Quality of Life / psychology
  • Risk Factors
  • Rural Health
  • Seroepidemiologic Studies
  • Sexual Partners / psychology

Substances

  • Antibodies, Viral