More on: endoplasmic reticulum loop VKORC1 substitutions cause warfarin resistance but do not diminish gamma-carboxylation of the vitamin K-dependent coagulation factors

J Thromb Haemost. 2011 May;9(5):1093-5. doi: 10.1111/j.1538-7836.2011.04249.x.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Anticoagulants / pharmacology
  • Atrial Fibrillation / blood
  • Atrial Fibrillation / therapy
  • Carbon-Carbon Ligases / metabolism
  • Endoplasmic Reticulum / metabolism*
  • Female
  • Humans
  • Male
  • Mixed Function Oxygenases / genetics*
  • Phenotype
  • Vitamin D / metabolism
  • Vitamin K Epoxide Reductases
  • Warfarin / pharmacology*

Substances

  • Anticoagulants
  • Vitamin D
  • Warfarin
  • Mixed Function Oxygenases
  • VKORC1 protein, human
  • Vitamin K Epoxide Reductases
  • Carbon-Carbon Ligases
  • glutamyl carboxylase