Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication

Antonella Esposito; Valentina Conti; Maria Cagliuso; Daniele Pastori; Alessandra Fantauzzi; Ivano Mezzaroma

doi:10.1186/1742-6405-8-9

Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication

AIDS Res Ther. 2011 Mar 1:8:9. doi: 10.1186/1742-6405-8-9.

Authors

Antonella Esposito^#¹, Valentina Conti^#¹, Maria Cagliuso^#¹, Daniele Pastori^#², Alessandra Fantauzzi^#¹, Ivano Mezzaroma¹

Affiliations

¹ Department of Clinical Medicine, "Sapienza"- University of Rome, Rome, Italy.
² Department of Experimental Medicine, "Sapienza"- University of Rome, Rome, Italy.

^# Contributed equally.

Abstract

In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred during a phase of uncontrolled viral replication combined with a severe immunodeficiency and resolved by an effective HAART are described, focusing on the etio-pathogenetic role possibly played by HIV-1 infection.