GlycoPEGylated rFVIIa (N7-GP) has a prolonged hemostatic effect in hemophilic mice compared with rFVIIa

J Thromb Haemost. 2011 May;9(5):1070-2. doi: 10.1111/j.1538-7836.2011.04252.x.
No abstract available

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Animals
  • Area Under Curve
  • Blood Coagulation
  • Disease Models, Animal
  • Factor VIIa / therapeutic use*
  • Glycosylation
  • Hemophilia A / blood*
  • Hemophilia A / therapy*
  • Hemostasis*
  • Humans
  • Mice
  • Polyethylene Glycols / chemistry*
  • Recombinant Proteins / therapeutic use
  • Thrombelastography / methods
  • Time Factors

Substances

  • Recombinant Proteins
  • Polyethylene Glycols
  • recombinant FVIIa
  • Factor VIIa