Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes

Angew Chem Int Ed Engl. 2011 Mar 7;50(11):2554-8. doi: 10.1002/anie.201006887. Epub 2011 Feb 18.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Base Sequence
  • Cyclic AMP Response Element-Binding Protein / chemistry
  • Cyclic AMP Response Element-Binding Protein / drug effects
  • Cyclic AMP Response Element-Binding Protein / metabolism*
  • Cyclization
  • DNA / chemistry*
  • DNA / metabolism*
  • Molecular Sequence Data
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Organometallic Compounds / pharmacology
  • Platinum / chemistry*
  • Protein Binding / drug effects
  • Thermodynamics

Substances

  • Antineoplastic Agents
  • Cyclic AMP Response Element-Binding Protein
  • Organometallic Compounds
  • Platinum
  • DNA