Abstract
The first case of carbapenemase-producing Enterobacteriaceae in Italy was reported in 2009. We performed a study over a period of seven months in 2010 to survey the circulation of Klebsiella pneumoniae carbapenemases (KPC) ina 1,500-bed university hospital in northern Italy and report the presence and rapid increase of these multidrug-resistant bacteria. The results raise a major concern about these pathogens and demonstrate the urgent need for infection control and antibiotic stewardship programmes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / metabolism*
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Carbapenems / pharmacology*
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Drug Resistance, Multiple, Bacterial*
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Hospital Bed Capacity, 500 and over
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Hospitalization / statistics & numerical data
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Hospitals, University
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Humans
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Incidence
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Italy / epidemiology
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Klebsiella Infections / drug therapy
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Klebsiella Infections / epidemiology
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Klebsiella Infections / microbiology
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Klebsiella pneumoniae / drug effects*
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Klebsiella pneumoniae / enzymology
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Klebsiella pneumoniae / genetics
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Klebsiella pneumoniae / isolation & purification*
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Microbial Sensitivity Tests
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Phenotype
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Polymerase Chain Reaction
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Population Surveillance
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beta-Lactamases / metabolism*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Carbapenems
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beta-Lactamases
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carbapenemase