Comparison of different IVIg preparations on IL-17 production by human Th17 cells

Mohan S Maddur; Srini V Kaveri; Jagadeesh Bayry

doi:10.1016/j.autrev.2011.02.007

Comparison of different IVIg preparations on IL-17 production by human Th17 cells

Autoimmun Rev. 2011 Oct;10(12):809-10. doi: 10.1016/j.autrev.2011.02.007. Epub 2011 Mar 2.

Authors

Mohan S Maddur¹, Srini V Kaveri, Jagadeesh Bayry

Affiliation

¹ Unité 872, Institut National de la Santé et de la Recherche Médicale Paris, F-75006, France.

PMID: 21376142
DOI: 10.1016/j.autrev.2011.02.007

Abstract

Variations in intravenous immunoglobulin (IVIg) products are a common feature. In this report, we compared the effect of different IVIg products on IL-17 production by human Th17 cells. We found that irrespective of products, IgGs of all IVIg preparations were equally effective in inhibiting the production of IL-17A from Th17 cells.

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Differentiation / drug effects
Cells, Cultured
Humans
Immunoglobulins, Intravenous / pharmacology*
Interleukin-17 / biosynthesis*
Lymphocyte Activation / drug effects
Th17 Cells / cytology
Th17 Cells / immunology*
Th17 Cells / metabolism*

Substances

Immunoglobulins, Intravenous
Interleukin-17