Lack of association of the RTN4R genetic variations with risk of schizophrenia and SPEM abnormality in a Korean population

Charisse Flerida A Pasaje; Joon Seol Bae; Byung-Lae Park; Chul Soo Park; Bong-Jo Kim; Cheol-Soon Lee; Jae Won Kim; Woo Hyuk Choi; Tae-Min Shin; In Song Koh; Ihn-Geun Choi; Sung-Ll Woo; Hyoung Doo Shin

doi:10.1016/j.psychres.2011.02.006

Lack of association of the RTN4R genetic variations with risk of schizophrenia and SPEM abnormality in a Korean population

Psychiatry Res. 2011 Sep 30;189(2):312-4. doi: 10.1016/j.psychres.2011.02.006. Epub 2011 Mar 5.

Authors

Charisse Flerida A Pasaje¹, Joon Seol Bae, Byung-Lae Park, Chul Soo Park, Bong-Jo Kim, Cheol-Soon Lee, Jae Won Kim, Woo Hyuk Choi, Tae-Min Shin, In Song Koh, Ihn-Geun Choi, Sung-Ll Woo, Hyoung Doo Shin

Affiliation

¹ Department of Life Science, Sogang University, Seoul, Republic of Korea.

PMID: 21377214
DOI: 10.1016/j.psychres.2011.02.006

Abstract

This study examined the association of the reticulon 4 receptor (RTN4R) gene with schizophrenia and smooth pursuit eye movement (SPEM) abnormality in a Korean population. Although we failed to provide convincing evidence that RTN4R is associated with schizophrenia development and SPEM impairment, our findings may be useful for further genetic studies.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Electrooculography / methods
Female
GPI-Linked Proteins / genetics
Genetic Predisposition to Disease / genetics
Genome-Wide Association Study
Humans
Male
Myelin Proteins / genetics*
Nogo Receptor 1
Ocular Motility Disorders / genetics*
Polymorphism, Single Nucleotide / genetics*
Pursuit, Smooth / genetics*
Receptors, Cell Surface / genetics*
Regression Analysis
Republic of Korea
Risk Factors
Schizophrenia / genetics*

Substances

GPI-Linked Proteins
Myelin Proteins
Nogo Receptor 1
RTN4R protein, human
Receptors, Cell Surface