Uterine large granular lymphocytes: a possible role in embryonic implantation?

Am J Obstet Gynecol. 1990 Feb;162(2):308-10. doi: 10.1016/0002-9378(90)90375-h.

Abstract

Leukocytes in endometrium and decidua are phenotypically and morphologically similar to granulated lymphocytes at other mucosal surfaces. Although their exact functions are not known, we suggest they may have a role in the control of implantation and the transformation of the uterine vasculature by trophoblast on which the blood supply to the fetoplacental unit depends.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, Differentiation, T-Lymphocyte / analysis
  • CD3 Complex
  • Embryo Implantation / physiology
  • Embryo, Mammalian / immunology*
  • Female
  • Humans
  • Killer Cells, Natural / physiology
  • Lymphocytes / physiology*
  • Pregnancy
  • Receptors, Antigen, T-Cell / analysis
  • Uterus / immunology*

Substances

  • Antigens, Differentiation, T-Lymphocyte
  • CD3 Complex
  • Receptors, Antigen, T-Cell