[Subarachnoid hemorrhages form ruptured aneurysms as the presenting feature of lupus cerebral vasculitis]

Rev Med Interne. 2012 Feb;33(2):e10-3. doi: 10.1016/j.revmed.2011.02.006. Epub 2011 Mar 8.
[Article in French]

Abstract

Cerebral aneurysms secondary to cerebral vasculitis related to systemic lupus erythematosus are rare. We report a 31-year-old woman who presented with a lupus flare associated with inaugural generalized seizures. Computed tomography angiography showed subarachnoid hemorrhage by rupture of a cerebellar artery fusiform aneurysm. Later, despite the initiation of corticosteroids and cyclophosphamide, she presented a second cerebral hemorrhage due to the rupture of a new aneurysm in lenticulostriates arteries. The outcome was fatal. We discuss the frequency and management of this severe complication of systemic lupus erythematosus.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Aneurysm, Ruptured / diagnosis
  • Aneurysm, Ruptured / etiology*
  • Cerebral Angiography
  • Fatal Outcome
  • Female
  • Humans
  • Intracranial Aneurysm / complications
  • Intracranial Aneurysm / diagnosis
  • Intracranial Aneurysm / etiology*
  • Lupus Vasculitis, Central Nervous System / complications*
  • Lupus Vasculitis, Central Nervous System / diagnosis
  • Magnetic Resonance Imaging
  • Rupture, Spontaneous
  • Seizures / etiology
  • Subarachnoid Hemorrhage / diagnosis
  • Subarachnoid Hemorrhage / etiology*