A 37-year-old man was admitted to our hospital because of an abnormal nodular shadow in the right upper field on chest radiography. We conducted transbronchial biopsy (TBB) and the pathological diagnosis was granular cell tumor (GCT). We performed a right upper lobectomy. The pathological findings of surgical specimens showed that the tumor cell had microscopically invaded the vascular region, and p53 immunostaining was positive. GCT is usually benign, but there is always a possibility of malignancy, as was observed in the present case. It is necessary to conduct careful follow-up in such cases.