Anticalcification strategies to increase bioprosthetic valve durability

J Heart Valve Dis. 2011 Jan;20(1):37-44.

Abstract

In recent years, there has been a revival in the use of bioprosthetic valves as aortic substitutes. For example, during 2008 in Germany, among 12,397 patients who underwent isolated aortic valve procedures, 78% received a biological prosthesis and 21% a mechanical valve, while only 1% underwent valve repair. However, whilst this situation is the reverse of that during the 1990s, the question must be asked as to whether this is simply a fluctuating fashion, or a reflection of other factors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Aortic Valve / surgery*
  • Bioprosthesis*
  • Calcinosis / etiology
  • Calcinosis / prevention & control*
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation*
  • Heart Valve Prosthesis*
  • Humans
  • Patient Selection
  • Prosthesis Design
  • Prosthesis Failure*
  • Risk Assessment
  • Risk Factors
  • Time Factors