Reverse pseudohyperkalemia in heparin plasma samples from a patient with chronic lymphocytic leukemia

Clin Biochem. 2011 Jun;44(8-9):728-30. doi: 10.1016/j.clinbiochem.2011.03.026. Epub 2011 Mar 21.

Abstract

Objectives: To investigate the spurious high potassium results in heparin plasma.

Design and methods: Potassium values from heparin plasma, serum, and whole blood in a patient with chronic lymphocytic leukemia were determined and compared on chemistry and blood gas analyzers.

Results: Potassium levels were strikingly elevated in heparin plasma compared to serum or whole blood in which the potassium levels were surprisingly normal.

Conclusions: The phenomenon of reverse pseudohyperkalemia should be publicized.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Female
  • Humans
  • Hyperkalemia / blood*
  • Leukemia, Lymphocytic, Chronic, B-Cell / blood*
  • Plasma / chemistry*
  • Potassium / blood
  • Serum / chemistry*

Substances

  • Potassium