Abstract
Nocardia is 1 of the 5 main pathogens that infect chronic granulomatous disease patients. Despite aggressive antimicrobial therapy, medical treatment is not always successful and surgical resection of infected tissue has been intermittently required. We present 2 chronic granulomatous disease patients with severe Nocardia pneumonia whose pulmonary status worsened despite appropriate antimicrobials, but then improved clinically and radiographically with the addition of corticosteroids.
Publication types
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Case Reports
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Research Support, N.I.H., Intramural
MeSH terms
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Adolescent
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Adrenal Cortex Hormones / therapeutic use*
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Adult
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Anti-Bacterial Agents / therapeutic use
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Anti-Inflammatory Agents / therapeutic use
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Granulomatous Disease, Chronic / complications*
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Granulomatous Disease, Chronic / drug therapy
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Humans
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Male
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Nocardia Infections / diagnosis
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Nocardia Infections / drug therapy*
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Nocardia Infections / etiology
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Pneumonia, Bacterial / diagnosis
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Pneumonia, Bacterial / drug therapy*
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Pneumonia, Bacterial / etiology
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Treatment Outcome
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Young Adult
Substances
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Adrenal Cortex Hormones
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Anti-Bacterial Agents
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Anti-Inflammatory Agents