Biosynthesis of 2-Alkyl-4(1H)-quinolones in Pseudomonas aeruginosa: potential for therapeutic interference with pathogenicity

Chembiochem. 2011 Apr 11;12(6):850-3. doi: 10.1002/cbic.201100014. Epub 2011 Mar 18.
No abstract available

MeSH terms

  • 4-Quinolones / metabolism*
  • Bacterial Proteins / antagonists & inhibitors*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Drug Discovery
  • Pseudomonas aeruginosa / drug effects
  • Pseudomonas aeruginosa / enzymology*
  • Pseudomonas aeruginosa / pathogenicity
  • Quorum Sensing
  • Recombinant Proteins / antagonists & inhibitors
  • Recombinant Proteins / genetics
  • Recombinant Proteins / metabolism

Substances

  • 2-heptyl-4-quinolone
  • 4-Quinolones
  • Bacterial Proteins
  • Recombinant Proteins