Two hytrosaviruses, MdSGHV and GpSGHV, induce distinct cytopathologies in their respective host insects

J Invertebr Pathol. 2011 Jun;107(2):161-3. doi: 10.1016/j.jip.2011.03.006. Epub 2011 Mar 23.

Abstract

Recently, a new virus family (Hytrosaviridae) was proposed for double-stranded DNA viruses that cause salivary gland hypertrophy in their dipteran hosts. The two type species, MdSGHV and GpSGHV, induce similar gross pathology and share several morphological, biological, and molecular characteristics. This histological study revealed profound differences in the cytopathology of these viruses supporting their previously proposed placement in different genera.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cell Enlargement
  • Cell Nucleus / pathology
  • Cell Nucleus / ultrastructure
  • Cell Nucleus / virology
  • Cell Proliferation
  • DNA Viruses / physiology*
  • Host-Pathogen Interactions*
  • Houseflies / ultrastructure
  • Houseflies / virology*
  • Hypertrophy / pathology
  • Insect Viruses / physiology*
  • Salivary Glands / pathology*
  • Salivary Glands / ultrastructure
  • Salivary Glands / virology
  • Tsetse Flies / ultrastructure
  • Tsetse Flies / virology*
  • Virion / physiology
  • Virion / ultrastructure