An in vitro system for measuring the transdermal voltage and molecular flux across the skin in real time

Methods Mol Med. 2000:37:407-36. doi: 10.1385/1-59259-080-2:407.

Abstract

In many in vitro transdermal drug delivery experiments, the skin is placed within a permeation chamber, and measurements are taken every hour or so. However, during skin electroporation, significant molecular transport can occur within the first few minutes (1).