Onycho-pachydermatit with extensive bone marrow edema predominant in the metacarpals: a "forme fruste" of POPP?

Rheumatol Int. 2012 May;32(5):1449-52. doi: 10.1007/s00296-011-1914-y. Epub 2011 Mar 30.

Abstract

Psoriatic onycho-pachydermo-osteo/periostitis (POPP) syndrome is a rare form of psoriatic arthritis with a combination of (i) psoriatic onychodystrophy, (ii) connective tissue thickening, and (iii) periostitis of the distal phalanges. The treatment of the condition has generally been reported to be unsatisfactory with the traditional regimes. Here, we describe a case whom we believe is one presentation of POPP with extensive bone marrow edema of metacarpal bones without distinctive periostitis.

Publication types

  • Case Reports

MeSH terms

  • Arthritis, Psoriatic / diagnosis*
  • Arthritis, Psoriatic / drug therapy
  • Arthritis, Psoriatic / pathology
  • Bone Marrow Diseases / diagnosis*
  • Bone Marrow Diseases / drug therapy
  • Bone Marrow Diseases / pathology
  • Connective Tissue Diseases / diagnosis*
  • Connective Tissue Diseases / drug therapy
  • Connective Tissue Diseases / pathology
  • Drug Therapy, Combination
  • Edema / diagnosis*
  • Edema / drug therapy
  • Edema / pathology
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Magnetic Resonance Imaging
  • Male
  • Metacarpal Bones / diagnostic imaging
  • Metacarpal Bones / drug effects
  • Metacarpal Bones / pathology*
  • Nail Diseases / diagnosis*
  • Nail Diseases / drug therapy
  • Nail Diseases / pathology
  • Periostitis / diagnosis*
  • Periostitis / drug therapy
  • Periostitis / pathology
  • Syndrome
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult

Substances

  • Immunosuppressive Agents