Effects of race on albuminuria and risk of cardiovascular and kidney disease

Expert Rev Cardiovasc Ther. 2011 Feb;9(2):245-9. doi: 10.1586/erc.10.185.

Abstract

The literature describing the relationship between urinary protein excretion and risk of cardiovascular disease and renal disease is rapidly proliferating. Several studies have demonstrated racial differences in the relationship between albuminuria and associated disorders. The purpose of this article is to summarize the effects of race on the relationship between albuminuria and renal and cardiovascular disease risk, propose explanatory hypotheses, and suggest directions for future investigation.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Albuminuria / ethnology
  • Albuminuria / genetics*
  • Albuminuria / physiopathology
  • Apolipoprotein A-I / genetics
  • Biomarkers / urine
  • Cardiovascular Diseases / ethnology*
  • Cardiovascular Diseases / genetics*
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / urine
  • Genetic Predisposition to Disease
  • Humans
  • Prevalence
  • Renal Insufficiency / ethnology*
  • Renal Insufficiency / genetics*
  • Renal Insufficiency / physiopathology
  • Renal Insufficiency / urine
  • Risk Factors
  • United States / epidemiology

Substances

  • APOA1 protein, human
  • Apolipoprotein A-I
  • Biomarkers