Healing time of radial forearm free flap donor sites after preoperative tissue expansion: randomized controlled trial

J Otolaryngol Head Neck Surg. 2011 Feb:40 Suppl 1:S20-7.

Abstract

Objective: The objective of this study is to test the hypothesis that using a simple and inexpensive preoperative tissue expansion device for radial forearm free flap donor sites will result in a significant reduction in healing time and reduced postoperative pain compared to unexpanded radial forearm free flap donor site skin.

Methods: Twenty-nine patients were enrolled and randomized to either the treatment (tissue pre-expansion) or the control group. An intention-to-treat analysis was used. Healing time was recorded for all patients. The Short Form McGill Pain Questionnaire was used to record arm pain and overall surgical pain 1 week postsurgery.

Results: The mean (95% CI) healing time was 5.7 (3.9-7.6) days for the treatment group and 32.5 (12.2-53.0) days for the control group (p < .001). Overall surgical pain (p < .001) was significantly lower in the treatment group. There was no significant difference in donor site arm pain (p < .2).

Conclusion: Using a simple, noninvasive method of preoperative tissue expansion results in both clinically and statistically significant reductions in healing time and postoperative pain.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Female
  • Follow-Up Studies
  • Forearm / surgery*
  • Free Tissue Flaps*
  • Head and Neck Neoplasms / surgery
  • Humans
  • Living Donors*
  • Male
  • Middle Aged
  • Pain, Postoperative / diagnosis
  • Pain, Postoperative / prevention & control*
  • Prospective Studies
  • Time Factors
  • Tissue Expansion / methods*
  • Treatment Outcome
  • Wound Healing*