Expression of gamma/delta T cell receptors on lymphocytes from the lactating mammary gland

J Exp Med. 1990 Oct 1;172(4):1263-6. doi: 10.1084/jem.172.4.1263.

Abstract

gamma/delta cells were at least four times more frequent in lactating mouse mammary glands than among T cells of the most proximal lymph nodes. Two-color staining of freshly isolated T cells and a study of clonally expressed gamma/delta receptors on hybridomas further revealed that the mammary gamma/delta population is heterogeneous, including at least three different subsets, among them cells expressing V gamma 5, V gamma 4 together with V delta 4, or none of these V regions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Female
  • Lactation*
  • Lymphocytes / immunology*
  • Mammary Glands, Animal / immunology*
  • Mice
  • Mice, Inbred C3H
  • Mice, Inbred C57BL
  • Molecular Sequence Data
  • Receptors, Antigen, T-Cell / analysis*
  • Receptors, Antigen, T-Cell, gamma-delta
  • T-Lymphocytes / immunology*

Substances

  • Receptors, Antigen, T-Cell
  • Receptors, Antigen, T-Cell, gamma-delta