A highly organocatalytic stereoselective double Michael reaction: efficient construction of optically enriched spirocyclic oxindoles

Chem Commun (Camb). 2011 May 21;47(19):5593-5. doi: 10.1039/c1cc11223f. Epub 2011 Apr 1.

Abstract

An effective double Michael reaction has been disclosed to access spirocyclic oxindoles in high yields (up to 98%) and excellent enantioselectivities (up to 98% ee).